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Sample ER Protocol for Identifying Iatrogenic Botulism

  • Megan McCue
  • Apr 26
  • 1 min read

Updated: Apr 29


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Created by Megan McCue:

***THIS IS NOT MEDICAL ADVICE; IT IS A SAMPLE PROTOCOL THAT HOSPITALS CAN USE/EDIT IN ORDER TO POTENTIALLY IDENTIFY CASES OF IATROGENIC BOTULISM***


If a patient presents to the emergency room with a sudden and new onset of at least 2 of the following:   

  • Dizziness

  • Blurry Vision

  • Muscle weakness

  • Difficulty swallowing

  • Dry mouth

  • Anxiety

  • Cardiac complaints (elevated BP, chest pain/pressure)

  • Shortness of breath complaints (can have normal O2 sats)


ASK: Have you received Botox (or another botulinum toxin product) in the past month?


If the answer is no: continue normal evaluation

If the answer is yes: conduct blood work and testing as usual, and call your state health department, or the CDC’s 24/7 phone line to speak with a botulism expert:


770-488-7100


Differential diagnosis:

Iatrogenic botulism is often misdiagnosed as Guillain-Barre syndrome, myasethnia gravis, psychiatric conditions, and stroke. These medical conditions should be ruled out prior to an iatrogenic botulism diagnosis.



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