Sample ER Protocol for Identifying Iatrogenic Botulism
- Megan McCue
- Apr 26
- 1 min read
Updated: Apr 29

Created by Megan McCue:
***THIS IS NOT MEDICAL ADVICE; IT IS A SAMPLE PROTOCOL THAT HOSPITALS CAN USE/EDIT IN ORDER TO POTENTIALLY IDENTIFY CASES OF IATROGENIC BOTULISM***
If a patient presents to the emergency room with a sudden and new onset of at least 2 of the following:
Dizziness
Blurry Vision
Muscle weakness
Difficulty swallowing
Dry mouth
Anxiety
Cardiac complaints (elevated BP, chest pain/pressure)
Shortness of breath complaints (can have normal O2 sats)
ASK: Have you received Botox (or another botulinum toxin product) in the past month?
If the answer is no: continue normal evaluation
If the answer is yes: conduct blood work and testing as usual, and call your state health department, or the CDC’s 24/7 phone line to speak with a botulism expert:
770-488-7100
Differential diagnosis:
Iatrogenic botulism is often misdiagnosed as Guillain-Barre syndrome, myasethnia gravis, psychiatric conditions, and stroke. These medical conditions should be ruled out prior to an iatrogenic botulism diagnosis.
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